Pfizer Looks Past COVID With $43 Billion Deal for Cancer Drug Innovator Seagen

Pfizer Inc PFE.N struck a $43 billion deal for Seagen Inc SGEN.O to add innovative targeted therapies to its portfolio of cancer treatments as it braces for a steep fall in COVID-19 product sales and stiff competition for some top sellers. Monday’s deal, Pfizer’s biggest in a string of acquisitions following a once-in-a-lifetime cash windfall from its COVID-19 vaccine and pill, will add four approved cancer therapies with combined sales of nearly $2 billion in 2022. Washington-based Seagen is a pioneer of antibody-drug conjugates, which work like “guided missiles” designed for a targeted destructive effect and spare healthy cells. The deal helps Pfizer move into an area “that it is more protected from regulators, patent perspectives and market dynamics,” Chief Executive Officer Albert Bourla said in a conference call.  Seagen, Bourla said, is set to benefit from out-of-pocket health care spending caps for older Americans under President Joe Biden’s Inflation Reduction Act (IRA), meaning more patients could have access to the company’s expensive treatments. A focus on complex biotech medicines also provides a longer exclusivity on the market versus pills before becoming subject to government price limits under the IRA, he said. Pfizer will pay $229 in cash per Seagen share, a 32.7% premium to Friday’s closing price. Seagen’s shares rose to $200 in early trading. The latest deal comes as Pfizer seeks to mitigate an anticipated $17 billion hit to revenue by 2030 from patent expirations for top drugs and decline in demand for its COVID products. The drugmaker …

WHO’s Tedros: Finding COVID-19 Origins Is Moral Imperative

Discovering the origins of COVID-19 is a moral imperative and all hypotheses must be explored, the head of the World Health Organization said, in the clearest indication yet that the U.N. body remains committed to finding how the virus arose. A U.S. agency was reported by The Wall Street Journal to have assessed the pandemic had likely been caused by an unintended Chinese laboratory leak, raising pressure on the WHO to come up with answers. Beijing denies the assessment which could soon become public after the U.S. House of Representatives voted this week to declassify it. “Understanding #COVID19’s origins and exploring all hypotheses remains: a scientific imperative, to help us prevent future outbreaks [and] a moral imperative, for the sake of the millions of people who died and those who live with #LongCOVID,” Tedros Adhanom Ghebreyesus said on Twitter late on Saturday.   He was writing to mark three years since the WHO first used the word “pandemic” to describe the global outbreak of COVID-19. Activists, politicians and academics said in an open letter this weekend that the focus of the anniversary should be on preventing a repeat of the unequal COVID-19 vaccine rollout, saying this led to at least 1.3 million preventable deaths. In 2021, a WHO-led team spent weeks in and around Wuhan, China where the first human cases were reported and said in a joint report that the virus had probably been transmitted from bats to humans through another animal, but further research was needed. China has …

Study: Prostate Cancer Treatment Can Wait for Most Men

Researchers have found long-term evidence that actively monitoring localized prostate cancer is a safe alternative to immediate surgery or radiation. The results, released Saturday, are encouraging for men who want to avoid treatment-related sexual and incontinence problems, said Dr. Stacy Loeb, a prostate cancer specialist at NYU Langone Health who was not involved in the research. The study directly compared the three approaches — surgery to remove tumors, radiation treatment and monitoring. Most prostate cancer grows slowly, so it takes many years to look at the disease’s outcomes. “There was no difference in prostate cancer mortality at 15 years between the groups,” Loeb said. And prostate cancer survival for all three groups was high — 97% regardless of treatment approach. “That’s also very good news.” The results were published Saturday in the New England Journal of Medicine and presented at a European Association of Urology conference in Milan, Italy. Britain’s National Institute for Health and Care Research paid for the research. Men diagnosed with localized prostate cancer shouldn’t panic or rush treatment decisions, said lead author Dr. Freddie Hamdy of the University of Oxford. Instead, they should “consider carefully the possible benefits and harms caused by the treatment options.” A small number of men with high-risk or more advanced disease do need urgent treatments, he added. Researchers followed more than 1,600 U.K. men who agreed to be randomly assigned to get surgery, radiation or active monitoring. The patients’ cancer was confined to the prostate, a walnut-sized gland that’s part of …

Pandemic 3 Years Later: Has COVID-19 Won?

On the third anniversary of the COVID-19 pandemic, the virus is still spreading, and the death toll is nearing 7 million worldwide. Yet most people have resumed their normal lives, thanks to a wall of immunity built from infections and vaccines. The virus appears here to stay, along with the threat of a more dangerous version sweeping the planet. “New variants emerging anywhere threaten us everywhere,” said virus researcher Thomas Friedrich of the University of Wisconsin-Madison. “Maybe that will help people to understand how connected we are.” Saturday marks three years since the World Health Organization first called the outbreak a pandemic, March 11, 2020, and the United Nation’s health organization says it’s not yet ready to say the emergency has ended. The virus endures With the pandemic still killing 900 to 1,000 people a day worldwide, the stealthy virus behind COVID-19 hasn’t lost its punch. It spreads easily from person to person, riding respiratory droplets in the air, killing some victims but leaving most to bounce back without much harm. “Whatever the virus is doing today, it’s still working on finding another winning path,” said Dr. Eric Topol, head of Scripps Research Translational Institute in California. We’ve become numb to the daily death toll, Topol says, but we should view it as too high. Consider that in the United States, daily hospitalizations and deaths, while lower than at the worst peaks, have not yet dropped to the low levels reached during summer 2021 before the delta variant wave. At …

US Lifts COVID Test Requirement for Chinese Travelers

A requirement that travelers to the U.S. from China present a negative COVID-19 test before boarding their flights expired Friday after more than two months as cases in China have fallen. The restrictions were put in place December 28 and took effect January 5 amid a surge in infections in China after the nation sharply eased pandemic restrictions and as U.S. health officials expressed concerns that their Chinese counterparts were not being truthful to the world about the true number of infections and deaths. The requirement from the U.S. Centers for Disease Control and Prevention expired for flights leaving after 3 p.m. Eastern time Friday. When the restriction was imposed, U.S. officials also said it was necessary to protect U.S. citizens and communities because there was a lack of transparency from the Chinese government about the size of the surge or the variants that were circulating within China. The rules imposed in January require travelers to the U.S. from China, Hong Kong and Macau to take a COVID-19 test no more than two days before travel and provide a negative test before boarding their flight. The testing applies to anyone 2 years and older, including U.S. citizens. China saw infections and deaths surge after it eased back from its “zero COVID” strategy in early December after rare public protests of the policy that confined millions of people to their homes and sparked demands for President Xi Jinping to resign. But as China eased its strict rules, infections and deaths surged, …

NASA’s Artemis Moon Missions Promise Diverse Crews

By launching an unmanned capsule into space, sending it around the moon and bringing it back to Earth in November, NASA demonstrated how it will once again transport astronauts to the lunar surface — a core goal of the Artemis program. What remains to be seen is who will crew the first trips. “Everybody in the astronaut office has the background, the basic training and the qualifications to go do that mission, so everyone is hoping that their name gets called,” astronaut Stan Love told VOA during an interview at Kennedy Space Center ahead of the Artemis 1 launch. Love is among those being considered for a spot. Artemis 2, a manned mission to orbit but not land on the moon, could launch as early as 2024. Love said the Artemis crews will look different than those of the Apollo program during the 1960s and 1970s. “We are going to broaden our demographics, so it won’t just be white guys landing on the moon.” “We make our boss’ jobs actually challenging, we make his job hard because he’s got to pick some of us,” says astronaut Victor Glover, who could make history as the first person of color to reach the moon. The crew for Artemis 2 will be announced April 3, according to NASA Administrator Bill Nelson, who said the team will include three NASA astronauts and one member of the Canadian Space Agency. “I think all of us are ready, trained and capable of making this mission a …

African Ministers in Malawi Discuss Cholera Outbreaks

The World Health Organization has called for Africa to step up the fight against cholera, which in the last year killed more than 3,000 people in 12 African countries, with more than half the victims dying in Malawi’s record outbreak. The global health body and the Africa Centers for Disease Control and Prevention held a two-day emergency meeting on cholera this week in Malawi with ministers from 14 African countries. The two-day meeting ended Friday with a call for countries to take a holistic approach in improving issues of water, sanitation and health among their populations. A closing statement said more commitment was needed on surveillance and prevention to eliminate the deadly cholera bacteria, which is spread by dirty water. The participants also resolved that African countries need to start producing their own cholera vaccine. Dr. Ambrose Talisuna, WHO’s regional adviser for health security in Africa, said the continent continues to face cholera outbreaks despite past commitments to eliminate the disease. “They committed themselves in 2018 by Regional Framework for Africa but we are lagging behind, the milestones are lagging behind,” Talisuna said. “So we really want to revitalize cholera prevention and control sustainably in Africa.” Talisuna said 12 African countries have current cholera outbreaks, totaling some 130,000 cases, with more than 51,000 in Malawi. “This is just too much, and we don’t know how many countries will have cholera before the end of the year,” he said. “But the outbreak we see in Malawi is so far the largest …

La Nina, Which Worsens Hurricanes and Drought, Is Gone

After three nasty years, the La Nina weather phenomenon that increases Atlantic hurricane activity and worsens Western drought is gone, the National Oceanic and Atmospheric Administration (NOAA) said Thursday. That’s usually good news for the United States and other parts of the world, including drought-stricken northeast Africa, scientists said. The globe is now in what’s considered a “neutral” condition and probably trending to an El Nino in late summer or fall, said climate scientist Michelle L’Heureux, head of NOAA’s El Nino/La Nina forecast office. “It’s over,” said research scientist Azhar Ehsan, who heads Columbia University’s El Nino/La Nina forecasting. “Mother Nature thought to get rid of this one because it’s enough.” Global impact La Nina is a natural and temporary cooling of parts of the Pacific Ocean that changes weather worldwide. In the United States, because La Nina is connected to more Atlantic storms and deeper droughts and wildfires in the West, La Ninas often are more damaging and expensive than their more famous flip side, El Nino, experts said, and studies show. Generally, American agriculture is more damaged by La Nina than El Nino. If the globe jumps into El Nino, it means more rain for the Midwestern corn belt and grains in general and could be beneficial, said Michael Ferrari, chief scientific officer of Climate Alpha, a firm that advises investors on financial decisions based on climate. When there’s a La Nina, there are more storms in the Atlantic during hurricane season because it removes conditions that suppress …

US Requires New Info on Breast Density With All Mammograms

All U.S. women getting mammograms will soon receive information about their breast density, which can sometimes make cancer harder to spot. The new requirements, finalized Thursday by the Food and Drug Administration, are aimed at standardizing the information given to millions of women following scans to detect breast cancer. Regulators first proposed the changes in 2019; health care providers will have 18 months to comply with the policy. Some states already require that women receive information on breast density. About half of women over age 40 have dense breasts, with less fatty tissue and more connective and glandular tissue. That tissue appears white on X-rays, the same color as growths in the breast, making mammograms harder to read. Dense breast tissue is one of the factors that can increase a woman’s chances of developing cancer. Under the new rules, women with dense breasts will receive a written memo alerting them that their status “makes it harder to find breast cancer.” Those patients will also be directed to speak with their doctor about their results. Professional guidelines don’t specify next steps for women identified with dense breasts, but some physicians may recommend additional forms of scanning, including ultrasound or MRI. …

WHO Chief: Too Much Salt Can Kill You

Sodium is essential for the smooth functioning of muscles and nerves and maintaining the proper balance of water and minerals. But too much sodium in the diet can kill. “Almost 2 million deaths each year are associated with excessive sodium intake,” said Tedros Adhanom Ghebreyesus, director-general of the World Health Organization. “Too much sodium can lead to high blood pressure and increase the risk of cardiovascular diseases,” he said. “And yet globally, average sodium intake is more than double the WHO recommendation for adults of less than 2,000 milligrams per day, or 5 grams of salt.” That is equivalent to one teaspoon of salt a day. A WHO report launched Thursday explores for the first time the progress countries have made in implementing sodium intake reduction policies. A survey of WHO’s 194 member states showed “the world is off track to achieve its global target of reducing sodium intake by 30% by 2025.” The report finds that only 5% of WHO member states “are protected by mandatory and comprehensive sodium reduction policies,” and 73% of WHO member states “lack full range of implementation of such policies.” Francesco Branca, director of WHO’s Department of Nutrition for Health and Development, noted that reducing sodium intake is one of the most cost-effective ways to improve health and reduce the burden of non-communicable diseases “as it can avert a large number of cardiovascular events and deaths at very low program costs.” Cardiovascular diseases are the leading cause of death globally, claiming an estimated 17.9 …

What to Know About Prescription Drugs Promising Weight Loss

WeightWatchers, the 60-year-old diet firm, announced this week it would acquire a telehealth company whose providers prescribe anti-obesity drugs for growing numbers of eager online subscribers. The $132 million deal with Sequence is just the latest commercial push into the red-hot market for prescription drugs that promises significant weight loss. For months, the diabetes drug Ozempic has been touted on social media by celebrities, even though it’s not approved for weight loss. The demand for it sparked shortages. WeightWatchers will be introducing its roughly 3.5 million subscribers to a new generation of medications that go beyond behavioral changes like gym workouts and diet tracking. Obesity experts say the drugs may revolutionize treatment of the disease that affects 42% of American adults. Here’s a look at the promise of these new medications and cautions about their use. What are these new diet drugs? The drugs that have generated most buzz are from a class of medications called GLP-1 agonists. Two of the most popular, Ozempic and Wegovy, are different doses of the same drug, semaglutide. Ozempic has been used for six years to treat Type 2 diabetes and is not approved for weight loss. Wegovy was approved in 2021 to treat obesity in adults, and late last year to treat kids and teens 12 and older. Doctors prescribe the medications to people with diabetes alone, or to people who are obese or who are overweight with additional health problems. Most of these types of drugs are delivered through weekly injections. Supply …

Plastic Entering Oceans Could Nearly Triple by 2040, Research Finds

Plastics entering the world’s oceans have surged by an unprecedented amount since 2005 and could nearly triple by 2040 if no further action is taken, according to research published on Wednesday. An estimated 171 trillion plastic particles were afloat in the oceans by 2019, according to peer-reviewed research led by the 5 Gyres Institute, a U.S. organization that campaigns to reduce plastic pollution. Marine plastic pollution could rise 2.6-fold by 2040 if legally binding global policies are not introduced, it predicted. The study looked at surface-level plastic pollution data from 11,777 ocean stations in six major marine regions covering the period from 1979 to 2019. “We’ve found an alarming trend of exponential growth in microplastics in the global ocean since the millennium,” Marcus Eriksen, co-founder of the 5 Gyres Group said in a statement. “We need a strong legally binding U.N. global treaty on plastic pollution that stops the problem at the source,” he added. Microplastics are particularly hazardous to the oceans, not only contaminating water but also damaging the internal organs of marine animals, which mistake plastic for food. Experts said the study showed that the level of marine plastic pollution in the oceans has been underestimated. “The numbers in this new research are staggeringly phenomenal and almost beyond comprehension,” said Paul Harvey, a scientist and plastics expert with Environmental Science Solutions, an Australian consultancy focused on pollution reduction. The United Nations kicked off negotiations on an agreement to tackle plastic pollution in Uruguay in November, with the aim …

France Reports Bird Flu in Foxes Near Paris, WOAH Says

France has reported an outbreak of highly pathogenic H5N1 bird flu among red foxes northeast of Paris, the World Organization for Animal Health (WOAH) said on Tuesday, as the spread of the virus to mammals raised global concerns. After three foxes were found dead in a nature reserve in Meaux near where gulls had died, one of the foxes was collected and tested, WOAH said in a report, citing French authorities. The World Health Organization last month described the bird flu situation as “worrying” due to the recent rise in cases in birds and mammals and that it was reviewing its global risk assessment in light of recent developments including cases of human transmission in Cambodia. Avian influenza, commonly called bird flu, has been spreading around the world in the past year, killing more than 200 million birds, sending egg prices rocketing and raising concern among governments about human transmission. The virus infected a cat in France in late December. It has also been detected in minks in Spain, foxes and otters in Britain, sea lions in Peru and grizzly bears in the United States. …

Four New Crew Members Arrive at International Space Station

The U.S. space agency NASA says two U.S. astronauts, another from the United Arab Emirates (UAE) and a Russian cosmonaut are safely aboard the International Space Station (ISS) after their Space-X Dragon crew capsule docked Friday with the orbiting laboratory. Video from NASA showed U.S. astronauts Stephen Bowen and Woody Hoburg, UAE astronaut Sultan Alneyadi and cosmonaut Andrey Fedyaev being greeted warmly by ISS crew members as they entered the space station about two hours after the docking. The 41-year-old Alneyadi is the second person from his country to fly to space and the first to launch from U.S. soil as part of a long-duration space station team. Space-X says the new crew members will spend six months on the station, where they will conduct more than 200 science experiments and technology demonstrations, NASA says the docking was delayed slightly as mission teams completed troubleshooting of a faulty docking hook sensor on the Dragon capsule. They verified all of the docking hooks were properly configured, and the docking process continued. The new crew members temporally expand the ISS crew to 11. They join the Expedition 68 crew, NASA astronauts Frank Rubio, Nicole Mann, and Josh Cassada, Japanese space agency, JAXA, astronaut Koichi Wakata, and Roscosmos cosmonauts Sergey Prokopyev, Dmitri Petelin, and Anna Kikina.  Some information for this report was provided by the Associated Press, Reuters and Agence France-Presse. …

One Month Later, Fallout from Toxic Train Accident Continues

One month after a freight train derailed in East Palestine, Ohio, sending tons of toxic chemicals into the air and prompting a temporary evacuation of the town, the fallout from the accident continues, both on the ground where local residents complain of lingering effects, and in Washington, where the Biden administration is under assault from conservatives over the federal response. There were no injuries reported as a result of the accident, but residents of the area nearby are complaining of a mix of symptoms that may be related to chemical exposure, including headaches, breathing difficulties and skin rashes. This is despite assertions by state and federal environmental officials who say they have tested air and water samples and have found no evidence of harmful levels of dangerous chemicals. Contractors have removed millions of gallons of toxic liquids and hundreds of tons of contaminated solid waste from the crash site and affected areas. However, some experts have questioned the thoroughness of the testing being conducted, and have warned that a larger and more extensive effort is necessary. In Washington, Republicans have used the accident to lash out at the Biden administration and its officials, calling the federal response to the disaster insufficient, despite Ohio’s Republican governor, Mike DeWine, saying publicly that he has “no complaints” about the federal response, and that his state is “getting the help we need.” In a more conspiratorial vein, members of conservative media organizations, including popular Fox News host Tucker Carlson, have worked to inject the …

Carbon Dioxide Emissions Reached a Record High in 2022

Communities around the world emitted more carbon dioxide in 2022 than in any other year on records dating to 1900, a result of air travel rebounding from the pandemic and more cities turning to coal as a low-cost source of power. Emissions of the climate-warming gas that were caused by energy production grew 0.9% to reach 36.8 gigatons in 2022, the International Energy Agency reported Thursday. (The mass of one gigaton is equivalent to about 10,000 fully loaded aircraft carriers, according to NASA.) Carbon dioxide is released when fossil fuels such as oil, coal or natural gas are burned to powers cars, planes, homes and factories. When the gas enters the atmosphere, it traps heat and contributes to the warming of the the climate. Extreme weather events intensified last year’s carbon dioxide emissions: Droughts reduced the amount of water available for hydropower, which increased the need to burn fossil fuels. And heat waves drove up demand for electricity. Thursday’s report was described as disconcerting by climate scientists, who warn that energy users around the world must cut emissions dramatically to slow the dire consequences of global warming. “Any emissions growth — even 1% — is a failure,” said Rob Jackson, a professor of earth system science at Stanford University and chairman of the Global Carbon Project, an international group. “We can’t afford growth. We can’t afford stasis. It’s cuts or chaos for the planet. Any year with higher coal emissions is a bad year for our health and for the …

SpaceX Launches Latest Space Station Crew to Orbit for NASA

Elon Musk’s rocket company SpaceX launched a four-person crew on a trip to the International Space Station early Thursday, with a Russian cosmonaut and United Arab Emirates astronaut joining two NASA crewmates on the flight. The SpaceX launch vehicle, consisting of a Falcon 9 rocket topped with an autonomously operated Crew Dragon capsule called Endeavour, lifted off at 12:34 a.m. EST (0534 GMT) from NASA’s Kennedy Space Center in Cape Canaveral, Florida. A live NASA webcast showed the 25-story-tall spacecraft ascending from the launch tower as its nine Merlin engines roared to life in billowing clouds of vapor and a reddish fireball that lit up the predawn sky. The launch was expected to accelerate the Crew Dragon to an orbital velocity of 28,164 kph, more than 22 times the speed of sound. The flight came 72 hours after an initial launch attempt was scrubbed in the final minutes of countdown early on Monday due to a clog in the flow of engine-ignition fluid. NASA said the problem was fixed by replacing a clogged filter and purging the system. The trip to the International Space Station (ISS), a laboratory orbiting some 420 kilometers above Earth, was expected to take nearly 25 hours, with rendezvous planned for about 1:15 a.m. EST (0615 GMT) Friday as the crew begins a six-month science mission in microgravity. Designated Crew 6, the mission marks the sixth long-term ISS team that NASA has flown aboard SpaceX since the private rocket venture founded by Musk — billionaire CEO …

Asteroid-Bashing Spacecraft ‘Phenomenally Successful,’ Studies Find

NASA’s DART spacecraft slammed into the asteroid Dimorphos at a spot between two boulders during last September’s first test of a planetary defense system, sending debris hurtling into space and changing the rocky, oblong-shaped object’s path a bit more than previously calculated.  Those were among the findings released by scientists on Wednesday in the most detailed account of the U.S. space agency’s proof-of-principle mission on using a spacecraft to change a celestial object’s trajectory — employing sheer kinetic force to nudge it off course just enough to keep Earth safe.  “The DART test was phenomenally successful. We now know that we have a viable technique for potentially preventing an asteroid impact if one day we had the need to,” said planetary scientist Terik Daly of the Johns Hopkins University Applied Physics Laboratory in Maryland, lead author of one of the DART studies published in the journal Nature.   The Double Asteroid Redirection Test (DART) spacecraft collided on September 26, 2022, at 22,530 kilometers per hour with Dimorphos, an asteroid about 150 meters in diameter, roughly 11 million kilometers from Earth. Dimorphos is a moonlet of Didymos, which is defined as a near-Earth asteroid and has a shape like a top spinning in space with a diameter of about 780 meters. Neither object imperils Earth.   “We were trying to change the amount of time that it took for Dimorphos to orbit around Didymos by colliding head-on with Dimorphos,” said Northern Arizona University planetary scientist Cristina Thomas, lead author of another of the …

Lilly Plans to Slash Some Insulin Prices, Expand Cost Cap

Eli Lilly will cut prices for some older insulins later this year and immediately give more patients access to a cap on the costs they pay to fill prescriptions.  The moves announced Wednesday promise critical relief to some people with diabetes who can face thousands of dollars in annual costs for insulin they need in order to live. Lilly’s changes also come as lawmakers and patient advocates pressure drugmakers to do something about soaring prices.  Lilly said it will cut the list prices for its most commonly prescribed insulin, Humalog, and for another insulin, Humulin, by 70% or more in the fourth quarter, which starts in October.  List prices are what a drugmaker initially sets for a product and what people who have no insurance or plans with high deductibles are sometimes stuck paying.  A Lilly spokeswoman said the current list price for a 10-milliliter vial of the fast-acting, mealtime insulin Humalog is $274.70. That will fall to $66.40.  Likewise, she said the same amount of Humulin currently lists at $148.70. That will change to $44.61.  Lilly CEO David Ricks said Wednesday that his company was making the changes to address issues that affect the price patients ultimately pay for its insulins.  He noted that discounts Lilly offers from its list prices often don’t reach patients through insurers or pharmacy benefit managers. High-deductible coverage can lead to big bills at the pharmacy counter, particularly at the start of the year when the deductibles renew.  “We know the current U.S. health …

US: 25 Million Lives Saved by AIDS Program

The head of a U.S. government program to fight AIDS, Dr. John Nkengasong, says that in its 20 years of existence the President’s Emergency Plan for AIDS Relief, or PEPFAR, has saved 25 million lives. PEPFAR, set up in 2003 under the administration of former U.S. president George W. Bush, has transformed the trajectory of HIV/AIDS, Nkengasong told reporters Tuesday while visiting South Africa. “Twenty-five million lives have been saved, 5.5 million children have been born free of HIV/AIDS, health systems have been strengthened in a remarkable way,” he said. Nkengasong, who comes from Cameroon, said there was once a “sense of hopelessness” in Africa, the continent worst-hit by HIV/AIDS, but since then countries’ economies have increased and life expectancy has improved. Some 95% of the total $110 billion spent through PEPFAR was spent on Africa as it bore the brunt of the disease, he said. “Before PEPFAR only 50,000 people, 50,000 people on the continent of Africa who were infected, were on treatment, 50,000. Today over 20 million people are receiving life-saving anti-retroviral therapy.” he said. Nkengasong said the infrastructure rolled out across Africa as part of the U.S. government program was also useful during the COVID-19 pandemic. The AIDS official said he was also “very positive” about the tools in the pipeline to combat HIV, including the roll out of pre-exposure prophylactics for HIV negative people that can be injected every three months and will stop the spread of new infections. …

Death Toll in Equatorial Guinea Marburg Outbreak Rises to 11 

Two more people in Equatorial Guinea have died of Marburg hemorrhagic fever, a cousin of the Ebola virus, bringing the toll of fatalities to 11, the authorities say. “Two days ago, the monitoring system recorded eight notifications, including the deaths of two people with symptoms of the disease,” Health Minister Mitoha Ondo’o Ayekaba said in a statement issued late Tuesday. Work is underway “to strengthen assessment of the spread of the epidemic,” said the statement, read on national television. “Forty-eight contact cases have been documented, four of whom have developed symptoms, and three who have been quarantined in hospital,” it added. The Marburg virus is a rare but highly dangerous pathogen that causes severe fever, often accompanied by bleeding and organ failure. It is part of the so-called filovirus family that also includes the Ebola virus, which has wreaked havoc in several previous outbreaks in Africa. The central African state announced on February 13 that nine people had died from Marburg between January 7 and February 7. The U.N.’s World Health Organization (WHO) held an emergency session the following day. The national authorities have declared a health alert in the remote northeastern province of Kie-Ntem province and in the neighboring district of Mongomo, which are located on the border with Cameroon and Gabon. Measures include a lockdown plan implemented in collaboration with the WHO. In their statement of February 13, the authorities had reported only three cases of infection in addition to the fatalities — individuals who were being isolated …

US Ambassador: China Should Be Candid About COVID Origins

The U.S. ambassador to China says Beijing needs to be more forthcoming about the origins of the COVID-19 pandemic, a day after reports that the U.S. Energy Department concluded the outbreak likely began because of a Chinese laboratory leak. Nicholas Burns told a U.S. Chamber of Commerce event by video link Monday that China needs to “be more honest about what happened three years ago in Wuhan with the origin of the COVID-19 crisis.” Wuhan is the Chinese city where the first cases of the novel coronavirus were reported in December 2019. His comments come a day after U.S. media reported that the Energy Department determined the pandemic likely arose from a laboratory leak in Wuhan. The department made its judgment in a classified intelligence report provided to the White House and key members of Congress, according to The Wall Street Journal, which first reported the development, citing people who read the report. The WSJ said the Energy Department intelligence agency was now the second U.S. intelligence agency after the FBI to conclude a Chinese lab leak was the probable cause of the pandemic, although U.S. spy agencies remain divided over the origins of the virus. White House national security spokesman John Kirby echoed that sentiment. “There has not been a definitive conclusion and consensus in the U.S. government on the origins of the COVID-19 pandemic,” Kirby told reporters Monday when asked about the WSJ report. The Energy Department assessment was made with “low confidence,” while the FBI conclusion was …

Child Immunization Vaccine Shortage Hits Ghana  

The Ghana Health Service says a shortage of routine vaccines for children blamed for a measles outbreak that infected 120 will be resolved within weeks. Health officials said the shortage of vaccines against polio, hepatitis B, and measles was caused by the depreciation of Ghana’s currency, the cedi. The Pediatric Society of Ghana warned childhood diseases could quickly spread if the vaccines were not soon made available.  For months, nursing mothers have been complaining of shortage of vaccines meant for babies from birth to at least 18 months. The situation became worse in February after major health facilities in 10 out of the 16 administrative regions of Ghana kept turning nursing mothers away due to erratic supply. Vivian Helemi said her baby girl missed one of the key vaccinations last month and the situation has not changed after combing three health centers on Monday. Like other mothers, Helemi is worried the shortage of the essential vaccines for infants will pose a threat to her child. “It has been frustrating moving from one hospital to another,” she told VOA. “I don’t know what could happen to my baby because she is yet to receive her second vaccination. I am confused because no one is telling me when the vaccines will be ready.” Timely vaccination of children, according to UNICEF, is a proven method for saving lives from vaccine-preventable diseases. It can also help attain some targets like the U.N. Sustainable Development Goal 3, which aims to ensure healthy lives and promote …