China-US Fentanyl Agreement Restarts Stalled Cooperative Fight Against Deadly Drug

U.S. President Joe Biden and Chinese President Xi Jinping agreed earlier this week that Beijing will crack down on companies in China that produce precursor chemicals for fentanyl, an agreement that Biden said would “save lives.” In exchange, the Biden administration agreed to lift sanctions on China’s Physical Evidence Identification Center of the Ministry of Public Security and the National Drug Laboratory. In May 2020, the U.S. Department of Commerce sanctioned the lab for allegedly participating in human rights violations against Uyghurs and other ethnic minorities in Xinjiang. China, which is the source of most fentanyl precursors used in the U.S., argued that U.S. export controls have “severely affected” China’s inspection and testing of fentanyl-related substances and impaired its “goodwill to help the U.S. in drug control,” according to the spokesperson of the Chinese Embassy in the United States. Although a cooperative effort to curb the supply of fentanyl brought some results over the years, enthusiasm dampened as tensions grew between China and the U.S. On Aug. 5, 2022 — after then-House Speaker Nancy Pelosi visited Taiwan, a self-governing island Beijing considers its own — China officially announced the suspension of anti-drug cooperation with the U.S. Here is some background to the Biden-Xi deal. What is fentanyl? According to the U.S. Centers for Disease Control and Prevention (CDC), fentanyl is 50 times more potent than heroin and 100 times more potent than morphine. It is a prescription drug in the United States used for treating severe pain. Illegally manufactured fentanyl “is …

World’s First Gene Therapy for Sickle Cell Disease Approved in Britain

Britain’s medicines regulator has authorized the world’s first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease in the U.K. In a statement Thursday, the Medicines and Healthcare Regulatory Agency said it approved Casgevy, the first medicine licensed using the gene editing tool CRISPR, which won its makers a Nobel prize in 2020. The agency approved the treatment for patients with sickle cell disease and thalassemia who are 12 years old and older. Casgevy is made by Vertex Pharmaceuticals (Europe) Ltd. and CRISPR Therapeutics. To date, bone marrow transplants, extremely arduous procedures that come with very unpleasant side effects, have been the only long-lasting treatment. “The future of life-changing cures resides in CRISPR based (gene-editing) technology,” said Dr. Helen O’Neill of University College London. “The use of the word ‘cure’ in relation to sickle cell disease or thalassemia has, up until now, been incompatible,” she said in a statement, calling the MHRA’s approval of gene therapy “a positive moment in history.” Both sickle cell disease and thalassemia are caused by mistakes in the genes that carry hemoglobin, the protein in red blood cells that carry oxygen.  In people with sickle cell — which is particularly common in people with African or Caribbean backgrounds — a genetic mutation causes the cells to become crescent-shaped, which can block blood flow and cause excruciating pain, organ damage, stroke and other problems. In people with thalassemia, the genetic mutation can cause …

Flu Soaring in 7 US States, Rising in Others, Health Officials Say

The U.S. flu season is under way, with at least seven states reporting high levels of illnesses and cases rising in other parts of the country, health officials say. The Centers for Disease Control and Prevention posted new flu data Friday, showing very high activity last week in Louisiana, and high activity in Alabama, Florida, Georgia, Mississippi, New Mexico and South Carolina. It was also high in the District of Columbia and Puerto Rico, the U.S. territory where health officials declared an influenza epidemic earlier this month. “We’re off to the races,” said Dr. William Schaffner, a Vanderbilt University infectious diseases expert. Traditionally, the winter flu season ramps up in December or January. But it took off in October last year, and is making a November entrance this year. Flu activity was moderate but rising in New York City, Arkansas, California, Maryland, New Jersey, North Carolina, Tennessee and Texas. And while flu activity has been high in Alaska for weeks, the state did not report data last week, so it wasn’t part of the latest count. Tracking during flu season relies in part on reports of people with flu-like symptoms who go to doctor’s offices or hospitals; many people with the flu are not tested, so their infections aren’t lab-confirmed. COVID-19 and other respiratory viruses can sometimes muddy the picture. Alicia Budd, who leads the CDC’s flu surveillance team, said several indicators are showing “continued increases” in flu. There are different kinds of flu viruses, and the version that’s been …

Melting Arctic Sea Ice Threatens Polar Bears  

In the Arctic, the impact of climate change is happening at an accelerated pace, with temperatures rising two to four times faster than the global average. “It’s called the polar amplification,” explains Vladimir Romanovsky, a geophysicist at the University of Alaska in Fairbanks. “Snow and ice reflect lots of energy back to space when ice and snow are melting, and the surface turns much darker. So this amount of energy will be absorbed by the surface, and it will make the surface warmer – at the same time making the atmosphere warmer as well.” Communities in circumpolar regions of Alaska are dealing with a triple challenge of climate change: coastal erosion, thawing of permafrost on which buildings and infrastructure stand, and, for some communities, the challenge of managing encounters with apex predators — polar bears pushed onshore. “An optimal habitat for polar bears now is basically absent, it’s disappeared,” says Todd Atwood, a wildlife biologist with the United States Geological Survey. He has been studying polar bears for the past 12 years and says melting sea ice makes it harder for bears to hunt seals. “That tends to be the trigger for bears to either stay with the sea ice as it retreats further over those deeper waters, or, for a growing proportion of the population to make the swim to shore.” In addition to the high risk of succumbing to sea conditions on a long swim, bears trying to adapt to life on land face an additional risk as …

Years of Uncertainty Ahead for Iceland Volcano Town

After a barrage of earthquakes that herald an impending volcanic eruption, some evacuated residents of the Icelandic town of Grindavik wonder if they will ever return. “There are going to be a lot of people who don’t want to go there. My mother said, ‘I never want to go there again,’” Eythor Reynisson, who was born and raised in Grindavik, told AFP. The fishing port of 4,000 people on Iceland’s south coast was evacuated on November 11 after magma shifting under the Earth’s crust caused hundreds of earthquakes — a warning of a likely volcanic eruption. Thousands of smaller tremors have shaken the region since. With massive crevices ripping roads apart and buildings’ concrete foundations shattered, the once picturesque Grindavik now resembles a war zone. The damage to the town hall will take months to repair. Long-term threat Even if the magma flow stops and no eruption occurs, “there is the issue of whether one should live in a town like this,” Freysteinn Sigmundsson, a geophysicist at the University of Iceland, told AFP. The Reykjanes peninsula had not experienced an eruption for eight centuries until 2021. Since then, three eruptions have struck — all in remote uninhabited areas — and volcanologists believe this may be the start of a new era of activity in the region. Sigmundsson warned that “a difficult period of uncertainty” lies ahead, as eruptions could happen in the coming years. That has left residents wondering whether it is worth rebuilding their homes. Sigmundsson said that for …

Pastoralists Modernizing to Cope With Climate Change, New Lifestyles

The moon glowed in the predawn Mongolia sky as Agvaantogtokh and his family prepared for another big move. On horseback, he rode to a well with nearly a thousand sheep and goats. Occasionally, he and his wife, Nurmaa, stopped to help struggling young ones, weak after a harsh winter. Thousands of miles away in Senegal, Amadou Altine Ndiaye’s family led livestock through a sparse African savannah. Horses and donkeys pulled a four-cart caravan along dirt paths in sweltering heat. Cattle followed. The family believed the next village would be richer with vegetation. “I was born into pastoralism, and since then I’ve known only that,” said Ndiaye, 48, a member of the Muslim Fulani ethnic group who learned the ways of herding alongside his elders. “It’s a source of pride.” More than 50 million people in Asia, Africa, the Middle East and elsewhere practice this way of life. As nomadic pastoralists, they keep domestic animals and move with them to seek fresh pastures — often selling some livestock for meat. Although pastoralism has sustained these populations for millennia, it faces mounting pressures from deteriorating environments, shrinking rangelands, and new generations who seek a less grueling life. At the same time, pastoralism is modernizing, with groups leveraging technology. The practice has survived for so long because it is designed to adapt to a changing environment — pastoralists move with animals to find fresh pasture and water, leaving behind fallow land to regrow. Experts say it’s a lesson that could help those who …

Progress in Childhood Cancer has Stalled for Blacks and Hispanics, US Report Says

Advances in childhood cancer are a success story in modern medicine. But in the past decade, those strides have stalled for Black and Hispanic youth, opening a gap in death rates, according to a new report published Thursday. Childhood cancers are rare and treatments have improved drastically in recent decades, saving lives. Death rates were about the same for Black, Hispanic and white children in 2001, and all went lower during the next decade. But over the next 10 years, only the rate for white children dipped a little lower. “You can have the most sophisticated scientific advances, but if we can’t deliver them into every community in the same way, then we have not met our goal as a nation,” said Dr. Sharon Castellino, a pediatric cancer specialist at Emory University’s Winship Cancer Institute in Atlanta, who had no role in the new report. She said the complexity of new cancers treatments such as gene therapy, which can cure some children with leukemia, can burden families and be an impediment to getting care. “You need at least one parent to quit their job and be there 24/7, and then figure out the situation for the rest of their children,” Castellino said. “It’s not that families don’t want to do that. It’s difficult.” More social workers are needed to help families file paperwork to get job-protected leave and make sure the child’s health insurance is current and doesn’t lapse. The overall cancer death rate for children and teenagers in the …

Frozen Library of Ancient Ice Tells Tales of Climate’s Past

How was the air breathed by Caesar, the Prophet Mohammed or Christopher Columbus? A giant freezer in Copenhagen holds the answers, storing blocks of ice with atmospheric tales thousands of years old. The Ice Core Archive, housing 25 kilometres (15 miles) of ice collected primarily from Greenland, is helping scientists understand changes in the climate. “What we have in this archive is prehistoric climate change, a record of man’s activities in the last 10,000 years,” glaciology professor Jorgen Peder Steffensen of the University of Copenhagen told AFP. Blocks of ice have been his passion for 43 years — and it was while drilling into Greenland’s ice sheet that he met his wife Dorthe Dahl-Jensen, also a top expert in the field of paleoclimatology. Steffensen has since 1991 managed the repository, one of the biggest in the world, with 40,000 blocks of ice stacked on long rows of shelves in large boxes. The frozen samples are unique, made up of compressed snow and not frozen water. “All the airspace between the snowflakes is trapped as bubbles inside (and) the air inside these bubbles is the same age as the ice,” Steffensen explained. The repository’s antechamber is similar to a library’s reading room: this is where scientists can examine the ice they have withdrawn from the main “library”, or storage room. But they must be quick: the temperature in the antechamber is kept at -18 degrees Celsius (-0.4F) — decidedly balmy compared to the -30C (-22F) in the storage room. Here, Steffensen …

US Approves SpaceX for 2nd Launch of Starship Super Heavy

The U.S. Federal Aviation Administration on Wednesday granted Elon Musk’s SpaceX a license to launch the company’s second test flight of its next-generation Starship and heavy-lift rocket from Texas, the agency said.  SpaceX said it was targeting Friday for a launch, saying a two-hour launch window opens at 7 a.m. Central Time (1300 GMT) and that local residents “may hear a loud noise” during the rocket’s ascent toward space.  “The FAA determined SpaceX met all safety, environmental, policy and financial responsibility requirements,” the agency, which oversees commercial launch sites, said in a statement.  SpaceX’s first attempt to send Starship to space was in April, when the rocket exploded mid-air four minutes after a liftoff that pulverized the company’s launchpad and flung sand and concrete chunks for miles.  Though Musk, SpaceX’s CEO and founder, hailed the Starship launch attempt as exceeding his expectations, it fell far short of its overall test objectives to reach space, complete nearly a full revolution around Earth, and reenter the atmosphere for a splashdown off a Hawaiian coast.  First the moon, eventually Mars Starship, standing taller than the Statue of Liberty at 120 meters and designed to be fully reusable, represents SpaceX’s next-generation workhorse rocket system capable of ferrying some 150 tons of satellites into space. Plans also call for the rocket system to be used to carry crews of humans to the moon, and eventually Mars.  The rocket is crucial for SpaceX’s increasingly dominant launch business. NASA, under a roughly $4 billion development contract with …

Nickel Miners, Environmentalists Learn to Live Together in Michigan

It began as a familiar old story. In the early 2000s, multinational mining giant Rio Tinto came to the wilds of Michigan’s Upper Peninsula to dig a nickel mine. Environmentalists feared pollution. The company promised jobs. The usual battle lines were drawn. The usual legal fights ensued. But this time, something different happened. The mining company invited a respected local environmental group to be an independent watchdog, conducting pollution testing that goes above and beyond what regulators require. More than a decade has passed, and no major pollution problems have arisen. Community opposition has softened. “I was fiercely opposed to the mine, and I changed,” said Maura Davenport, board chair of the Superior Watershed Partnership, the environmental group doing the testing. The agreement between the mining company and the environmentalists is working at a time when demand for nickel and other metals used in green technologies is on the rise, but the mining activity that supplies those metals faces fierce local resistance around the world. Historic mines, polluting history The shift to cleaner energy needs copper to wire electrical grids, rare earth elements for wind turbine magnets, lithium for electric vehicle batteries, nickel to make those batteries run longer, and more. Meeting the goals of the 2015 U.N. Paris climate agreement would mean a fourfold increase in demand for metals overall by 2040 and a 19-fold increase in nickel, according to the International Energy Agency. That means more mines. But mines rarely open anywhere in the world without controversy. Two …

Heat-related Deaths to Soar Nearly 400% by 2050 – Report

A new report says heat-related deaths will increase 370 percent by 2050 if global temperatures increase by 2 degrees Celsius over pre-industrial levels, as predicted.  The findings were part of a report published Wednesday in the medical journal Lancet’s annual assessment, known as the Coundown, on the effects of climate change on public health.   The Countdown found that the number of heat-related deaths among people aged 65 and older has risen 85% over the last decade compared to the years between 1991 and 2000.  The study found that people around the world were exposed to an average of 86 days of life-threatening high temperatures.   The study also projected that more than 500 million more people could be at risk for food insecurity by mid-century from droughts triggered by more frequent heatwaves. The international team of experts that conducted the Lancet study criticized the rise in fossil fuel production, helped by massive government subsidies and investments by private banks.   A study released last week by the U.N. Environment Program says 20 of the world’s major fossil fuel-producing nations are on track to produce about 110% more oil, gas and coal in 2030 than the amounts consistent with limiting global temperature rise to 1.5 degrees Celsius.  Holding down global temperatures to a 1.5 degree increase compared with pre-industrial levels was a key goal of the global climate pact signed in Paris in 2015.   The 20 countries in the report include Australia, Brazil, Russia, Saudi Arabia, the United Arab Emirates and the United …

Young Africans Hope to Address Climate Challenges Through Training Program

Fifty young innovators and leaders from 19 African countries attended a three-week leadership and professional development training program in Ghana’s capital, Accra. Sponsored by the U.S. government, the Young African Leaders Initiative, or YALI, program challenges them to find technology-focused social and business solutions to climate challenges. Isaac Kaledzi has more from Accra. …

Internal Documents Show the World Health Organization Paid Sexual Abuse Victims in Congo $250 Each

Earlier this year, the doctor who leads the World Health Organization’s efforts to prevent sexual abuse traveled to Congo to address the biggest known sex scandal in the U.N. health agency’s history, the abuse of well over 100 local women by staffers and others during a deadly Ebola outbreak. According to an internal WHO report from Dr. Gaya Gamhewage’s trip in March, one of the abused women she met gave birth to a baby with “a malformation that required special medical treatment,” meaning even more costs for the young mother in one of the world’s poorest countries. To help victims like her, the WHO has paid $250 each to at least 104 women in Congo who say they were sexually abused or exploited by officials working to stop Ebola. That amount per victim is less than a single day’s expenses for some U.N. officials working in the Congolese capital — and $19 more than what Gamhewage received per day during her three-day visit — according to internal documents obtained by The Associated Press. The amount covers typical living expenses for less than four months in a country where, the WHO documents noted, many people survive on less than $2.15 a day. The payments to women didn’t come freely. To receive the cash, they were required to complete training courses intended to help them start “income-generating activities.” The payments appear to try to circumvent the U.N.’s stated policy that it doesn’t pay reparations by including the money in what it calls …

Jill Biden to Lead New Initiative to Boost Federal Government Research into Women’s Health

The Biden administration on Monday announced a White House initiative to improve how the federal government approaches and funds research into the health of women, who make up more than half of the U.S. population but remain understudied and underrepresented in health research.  That underrepresentation can lead to big gaps in research and potentially serious consequences for the health of women across the country, Biden administration officials and others told reporters during a White House conference call to announce the new effort.  The White House Initiative on Women’s Health Research will be led by first lady Jill Biden and the White House Gender Policy Council.  President Joe Biden said he’s long been a believer in the “power of research” to help save lives and get high-quality health care to the people who need it. Surrounded by the first lady and other officials who will have a role in the government-wide effort, Biden signed paperwork Monday in the Oval Office to direct federal departments and agencies to begin their work.  “To achieve scientific breakthroughs and strengthen our ability to prevent, detect and treat diseases, we have to be bold,” the president said in a written statement. He said the initiative will “drive innovation in women’s health and close research gaps.”  Jill Biden said during the conference call that she met earlier this year with former California first lady and women’s health advocate Maria Shriver, who “raised the need for an effort inside and outside government to close the research gaps in …

Nepal Bans TikTok, Says It Disrupts Social Harmony

Nepal’s government decided to ban the popular social media app TikTok, saying Monday it was disrupting “social harmony” in the country. The announcement was made following a Cabinet meeting. Foreign Minister Narayan Prakash Saud said the app would be banned immediately. “The government has decided to ban TikTok as it was necessary to regulate the use of the social media platform that was disrupting social harmony, goodwill and flow of indecent materials,” Saud said. He said that to make social media platforms accountable, the government has asked the companies to register and open a liaison office in Nepal, pay taxes and abide by the country’s laws and regulations. It wasn’t clear what triggered the ban or if TikTok had refused to comply with Nepal’s requests. The company did not immediately respond to an email seeking comment. TikTok, owned by China’s ByteDance, has faced scrutiny in several countries because of concerns that Beijing could use the app to harvest user data or advance its interests. Countries including the United States, Britain and New Zealand have banned the app on government phones despite TikTok repeatedly denying that it has ever shared data with the Chinese government and would not do so if asked. Nepal has banned all pornographic sites in 2018. …

Cargo Standstill as Cyberattacks Close Australian Ports 

Several major Australian ports are resuming operations after shutting down due to a cyberattack. The ports are run by DP World Australia, one of the country’s biggest logistics companies. Authorities have not said who might be to blame. The shutdown of several terminals followed a cyberattack on Australia’s second largest port operator. DP World Australia said it was aware of malicious activity inside its computer network last Friday and shut down its systems in response. The logistics company handles about 40% of all freight into and out of Australia. Terminals in Brisbane, Melbourne, Sydney and Fremantle in Western Australia have been affected, leaving cargo and containers stranded on the docks. The specific nature of the intrusion has not been made public, but experts have suggested that hackers would have demanded a ransom. Authorities say that finding out who is responsible will take time. Australia’s National Cyber Security coordinator says the flow of goods into and out of the country is likely to be disrupted for days. Authorities have said a national crisis management response used during the COVID-19 pandemic, has been activated in response to the breach. The home affairs and cyber security minister, Clare O’Neil, told local media Monday that efforts are being made to ensure the company’s computer network can safely be reactivated. “DP World have been working with government to try to resolve this and in ways that will make sure that this does not impact as much as possible on Australians. It does show how vulnerable …

Russia to Limit Only VPN Services That Pose a ‘Threat’ to Security, State Media Say

Russia plans to block certain Virtual Private Networks (VPNs) and protocols that are deemed by a commission of experts to pose a threat, state news agency RIA reported, citing correspondence from the digital ministry. Demand for VPN services soared after Russia restricted access to some Western social media after President Vladimir Putin ordered troops into Ukraine in February 2022. A 2017 Russian law obliged providers of VPN technology to cooperate with the Russian authorities and to restrict access to content banned by Russia or be banned themselves. Many VPN services remain widely in use throughout Russia and there has been a public debate among lawmakers about how much further to go in blocking VPN services that still allow access to banned information but also a host of other information. RIA quoted a reply from the digital ministry to an address by lawmaker Anton Tkachev who had raised concerns about what he said were plans to essentially block all VPNs, a step he said would increase pressure on Russians by cutting them off from using some simple household appliances. “On the basis of a decision by the expert commission… the filtration of certain VPN services and VPN protocols can be carried out on the mobile communication network for foreign traffic which is identified as a threat,” RIA quoted the ministry as saying. RIA said that the ministry said that circumvention of restrictions on certain information was considered a threat. …

Australia Says Ports Operator Cyber Incident ‘Serious’

The Australian government on Sunday described as “serious and ongoing” a cybersecurity incident that forced ports operator DP World Australia to suspend operations at ports in several states since Friday. DP World Australia, which manages nearly half of the goods that flow in and out of the country, said it was looking into possible data breaches as well as testing systems “crucial for the resumption of normal operations and regular freight movement.” The breach halted operations at container terminals in Melbourne, Sydney, Brisbane and Western Australia’s Fremantle since Friday. “The cyber incident at DP World is serious and ongoing,” Home Affairs Minister Clare O’Neil said on social media platform X, formerly known as Twitter. A DP World spokesperson did not immediately respond to a Reuters request for comment on when normal operations would resume. The company, part of Dubai’s state-owned DP World, is one of a handful of stevedore industry players in the country. The Australian Federal Police said they were investigating the incident but declined to elaborate. Late Saturday, National Cyber Security Coordinator Darren Goldie, appointed this year in response to several major data breaches, said the “interruption” was “likely to continue for a number of days and will impact the movement of goods into and out of the country.” In the Asia-Pacific region, DP World says it employs more than 7,000 people and has ports and terminals in 18 locations. …