US Pharmacy Chains Reach Tentative Opioid Settlement

Three of the largest U.S. pharmacy chains — CVS, Walgreens and Walmart — are reported to have tentatively agreed to pay more than $13 billion to settle more than 3,000 state and local lawsuits involving the dispensing of opioid painkillers.  Sources close to the negotiations report CVS will pay $5 billion over 10 years, Walgreens will pay $5.7 billion over 15 years and Walmart will pay $3.1 billion, mostly up front. The sources remained anonymous as they were not authorized to speak publicly about the agreement.    In a statement released Wednesday, CVS Health said it has agreed it will pay approximately $5 billion — with $4.9 billion to states and political subdivisions and approximately $130 million to Native American tribes — over the next 10 years beginning in 2023.  In the statement, CVS Health Chief Policy Officer and General Counsel Thomas Moriarty said, “We are committed to working with states, municipalities and tribes, and will continue our own important initiatives to help reduce the illegitimate use of prescription opioids.”   The CVS statement included a list of initiatives it has undertaken to fight opioid abuse.   In the lawsuits, governments said pharmacies were filling prescriptions they should have flagged as inappropriate.  If the settlement is finalized, it would be the first nationwide deal with retail pharmacy companies and follows nationwide opioid settlements with drugmakers and distributors totaling more than $33 billion.  Opioids are natural, synthetic, or semi-synthetic chemicals used to reduce the intensity of pain signals and feelings of …

Strong RSV Vaccine Data Lifts Hopes After Years of Futility

New research shows vaccinating pregnant women helped protect their newborns from the common but scary respiratory virus called RSV that fills hospitals with wheezing babies each fall. The preliminary results buoy hope that after decades of failure and frustration, vaccines against RSV may finally be getting close. Pfizer announced Tuesday that a large international study found that vaccinating moms-to-be was nearly 82% effective at preventing severe cases of RSV in their babies’ most vulnerable first 90 days of life. At age 6 months, the vaccine still was proving 69% effective against serious illness — and there were no signs of safety problems in mothers or babies. “Moms are always giving their antibodies to their baby,” said virologist Kena Swanson, Pfizer’s vice president of viral vaccines. “The vaccine just puts them in that much better position” to form and pass on RSV-fighting antibodies. The vaccine quest isn’t just to protect infants. RSV is dangerous for older adults, too, and both Pfizer and rival GSK recently announced that their competing shots also proved protective for seniors. None of the findings will help this year when an early RSV surge already is crowding children’s hospitals. But they raise the prospect that one or more vaccines might become available before next fall’s RSV season. “My fingers are crossed,” said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. “We’re making inroads.” Tuesday’s data was reported in a press release and hasn’t been vetted by independent experts. Here’s a look at the long quest …

Battling Cholera, Lebanon Gets First Vaccines, Sharp Words, From France

Lebanon received a first batch of vaccines Monday to combat a worsening cholera outbreak – together with sharply worded criticism of its crumbling public health infrastructure from France, which facilitated the donation of the doses. By Sunday, cases of cholera – a disease typically spread through contaminated water, food or sewage – stood at 1,447, with 17 deaths, since the first were recorded in the country a month ago, Lebanon’s health ministry said. Lebanon had been cholera-free since 1993, but its public services are suffering under a brutal economic crisis now in its fourth year, while infighting among the country’s faction-riven elite has paralyzed its political institutions. The outbreak has reached Beirut, but authorities say most cases remain concentrated where it started in the northern town of Bebnine, where health authorities have set up an emergency field hospital. The vaccines would play “an essential role” in limiting the disease’s spread, Health Minister Firass Abiad told reporters in the capital as he announced the first batch. Standing next to Abiad, French ambassador Anne Grillo said the delivery comprised more than 13,000 doses. They had been donated by the philanthropic arm of French health care company Sanofi and the French government had facilitated their arrival to Lebanon. “The origins of this epidemic, in which public health is at stake, must also be treated,” Grillo told reporters. The outbreak was “a new and worrying illustration of the critical decline in public provision of access to water and sanitary services in Lebanon.” In the …

Observers: China’s Chip Talent Hurdle Worsens After Layoffs at US Firm Marvell

Santa Clara, California-based chip producer Marvell Technology has confirmed that it is eliminating research and development staffs in China – the third U.S. chipmaker that has done so this year as the U.S.-China tech rivalry intensifies. Observers say this will hobble China’s chip ambitions and worsen its talent shortfall in the field of designing and manufacturing cutting-edge computer chips. “China is definitely going to be at a loss when it comes to American companies like Marvell essentially redesigning their workforce, because China still hasn’t reached a point where it’s able to pump out the same level of chip talent as America or the UK or Israel,” Abishur Prakash, a co-founder at Center for Innovating the Future (CIF) in Canada told VOA over the phone. China becoming off-limits These tech giants are aware the era when companies could set up supply chains and move talent around the globe freely is coming to an end and “China is becoming off-limits for Western companies,” added Prakash, the author of five books including the latest one, titled “The World is Vertical: How Technology Is Remaking Globalization.” Marvell’s decision came weeks after the Biden administration, in early October, imposed additional curbs on China-bound exports of advanced chips, as well as the technology and equipment to produce 14-nanometer chips or better.  The new rules also prohibited “U.S. persons” including U.S. citizens and green card holders from working at Chinese chip firms, in an apparent move to stem the flow of U.S.-trained tech talent to China.  “In …

Australia Bans More Single-Use Plastics

On Tuesday, Nov. 1, Australia’s most populous state is banning a range of single-use plastic, including straws, cutlery and bowls. Polystyrene foam food containers are also banned under the new rules in New South Wales, along with some face, body and hair products that contain plastic micro beads.    Businesses that breach the regulations could face fines of tens of thousands of dollars.   Minister for Environment and Heritage James Griffin said in a statement in September that the ban was just the start of a “massive shift away from single-use plastic.”   He has predicted the ban would stop 2.7 billion items of plastic ending up as litter over the next 20 years.  The laws in New South Wales are part of a nationwide push to curb waste. State authorities in Queensland and Victoria will bring in similar bans next year.   Environmental campaigners have welcomed the laws but insist much more needs to be done. Australia currently recycles 16% of its plastic packaging, below the national target of 70%.    Shane Cucow of the Australian Marine Conservation Society told VOA that recycling needs to be improved, because “Every wrap, pack and snack at a supermarket these days is covered in plastic.” He added that, “We can get rid of some of those single-use plastics that are highly littered and regularly ending up in our oceans like cups and straws and take-away containers and plastic bags, and that is really important, but at the same time there is just so much plastic packaging …

Antibody Treatment Tested as New Tool Against Malaria

Research in Africa found a one-time dose of an experimental drug protected adults against malaria for at least six months, the latest approach in the fight against the mosquito-borne disease.  Malaria killed more than 620,000 people in 2020 and sickened 241 million, mainly children under 5 in Africa. The World Health Organization is rolling out the first authorized malaria vaccine for children, but it is about 30% effective and requires four doses.  The new study tested a very different approach — giving people a big dose of lab-made malaria-fighting antibodies instead of depending on the immune system to make enough of those same infection-blockers after vaccination. “The available vaccine doesn’t protect enough people,” said Dr. Kassoum Kayentao of the University of Sciences, Techniques and Technologies in Bamako, Mali, who helped lead the study in the villages of Kalifabougou and Torodo.  In those villages during malaria season, other research has shown, people are bitten by infected mosquitoes on average twice a day.  The experimental antibody, developed by researchers at the U.S. National Institutes of Health, was given by IV — difficult to deliver on a large scale. But the encouraging findings bode well for an easier-to-administer shot version from the same scientists that’s in early testing in infants, children and adults. The U.S. government research was published Monday in the New England Journal of Medicine and presented at a medical meeting in Seattle.  The antibody works by breaking the life cycle of the parasite, which is spread through mosquito bites. It …

China’s 3rd and Final Space Station Component Docks

China’s third and final module docked with its permanent space station Tuesday to further a decadeslong effort to maintain a constant crewed presence in orbit, as its competition with the United States grows increasingly fierce. The Mengtian module arrived at the Tiangong station early Tuesday morning, state broadcaster CCTV said, citing the China Manned Space Agency. Mengtian was blasted into space on Monday afternoon from the Wenchang Satellite Launch Center on the southern island province of Hainan. It was expected to take about 13 hours to complete the flight and docking mission. A large crowd of amateur photographers, space enthusiasts and others watched the lift-off from an adjoining beach. Many waved Chinese flags and wore T-shirts emblazoned with the characters for China, reflecting the deep national pride invested in the space program and the technological progress it represents. “The space program is a symbol of a major country and a boost to the modernization of China’s national defense,” said Ni Lexiong, a professor at Shanghai University of political science and law, underscoring the program’s close military links. “It is also a boost to the confidence of the Chinese people, igniting patriotism and positive energy,” Ni said. Mengtian, or “Celestial Dream,” joins Wentian as the second laboratory module for the station, collectively known as Tiangong, or “Celestial Palace.” Both are connected to the Tianhe core module where the crew lives and works. Like its predecessors, Mengtian was launched aboard a Long March-5B carrier rocket, a member of China’s most powerful family …