Pfizer: COVID-19 Pill Cuts Risk of Severe Disease by 89%

U.S. pharmaceutical company Pfizer announced Friday its new COVID-19 pill showed an 89% reduction in risk of COVID-19-related hospitalization or death in clinical trials and they plan to submit the drug to U.S. regulators for emergency use approval. In a release Friday, Pfizer said the latest clinical trials of its pill, Paxlovid, featured a randomized, double-blind study of non-hospitalized adult patients with COVID-19 who are at high risk of progressing to severe illness.  The company said interim analysis of the oral antiviral showed an 89% reduction in risk compared to a placebo in patients treated within three days of symptom onset.  Pfizer said it has received an independent data monitoring committee recommendation to pause enrollment in the Phase 3 trial due to the overwhelming efficacy demonstrated in the latest results.  The company plans to submit the data as part of its ongoing application to the FDA for Emergency Use Authorization as soon as possible.  Pfizer is now the second drug manufacturer to develop an oral treatment for COVID-19. U.S. company Merck last month introduced its COVID-19 pill, which clinical studies showed to provide a 50% reduction in hospitalizations and deaths due to COVID-19. It has been submitted to the FDA, and the federal agency is scheduled to rule on it late this month.  Currently, all COVID-19 treatments approved in the United States require injection or intravenous drip. Pills have the advantage of being distributed by pharmacies and taken at home.  Britain’s Medicines and Healthcare products Regulatory Agency approved Merck’s pill, …

UN Recap: October 31-November 5

Editor’s note: Here is a fast take on what the international community has been up to this past week, as seen from the United Nations perch. Leaders talk global warming in Glasgow  — World leaders met in Glasgow, Scotland, this week to try to halt global warming. But with some of the world’s biggest emitters like China and Russia skipping the conference, known as COP26, hopes dimmed that leaders will find a way to keep the world from warming more than the goal of 1.5 degrees Celsius this century. Hope Eroding as COP26 Climate Pledges Fall Short — Burning coal is the single biggest contributor to climate change. Phasing out its use between 2030 and 2040 is one of the United Nation’s most ambitious appeals. More than 40 countries made coal-related pledges on Thursday at COP26. COP26: Britain Hails Global Deals to End Coal but Plans New Mine — The world’s youth have the most at stake as the planet warms, and they have been vocal advocates for change. On Friday, they took center stage during Youth and Public Empowerment Day at COP26. ‘It’s Our Lives on the Line’, Young Marchers Tell UN Climate Talks  War crimes committed in northern Ethiopia — The conflict between the Ethiopian federal army and Tigrayan fighters in northern Ethiopia reached the one-year milestone this week. A report written by a joint investigative team from the United Nations and the Ethiopian Human Rights Commission was published Wednesday, saying all belligerents have committed atrocities during the …

Exodus of Foreign Internet Giants Strengthens China’s Homegrown Ecosystem

China now depends almost entirely on its own online content providers, as the number of big foreign companies in the market, such as Yahoo and LinkedIn, keeps dwindling, giving the government a boost in controlling the internet, analysts say. On Monday the Silicon Valley internet service provider Yahoo closed all of its services in China, following LinkedIn’s pullout announcement in October and earlier blockages of Google content. In an e-mailed statement, Yahoo cited an “increasingly challenging business and legal environment in China.” Many Yahoo services were largely blocked in China, where the email and search engine provider has operated since 1999. “My first reaction was, I didn’t know Yahoo was still alive in China,” said Danny Levinson, Beijing-based head of technology at the seed investment firm Matoka Capital. Domestic services flourish Chinese netizens seldom use Yahoo or other major Silicon Valley internet services, especially for media and communications, as domestic rivals have flourished over the past two decades. The government can handily monitor local providers for what it considers subversive content by calling in company managers for discipline. Chinese use China-based WeChat for the bulk of their daily communication, watch TikTok videos instead of YouTube and check China’s Baidu.com rather than Wikipedia. Alibaba, headquartered in Hangzhou, takes care of e-commerce, although foreign rivals can still get into China given their trade’s lack of political sensitivity. “They had all the ingredients in place,” said Kaiser Kuo, a U.S.-based podcaster who has worked in Chinese tech. “You had a really large, very fast-growing market. …

Young Activists to Take Spotlight for a Day at UN Climate Talks

Activists will take over the UN climate summit in Scotland on Friday, capping off a week of dizzying government speeches and pledges with a student march, youth-led presentations, and a giant iceberg shipped from Greenland to Glasgow’s River Clyde to dramatize the plight of the Arctic. UK organizers decided to hand the day over to civic groups in an acknowledgement of how young campaigners like Vanessa Nakate of Uganda and Greta Thunberg of Sweden have raised public understanding of climate change, and a nod to their stance that today’s youth must live with consequences of state decisions. “We’re expecting lots of people to come and join us in the streets and not only youth but also adults supporting youth, and adults that want climate action,” said Isabelle Axelsson, 20, an activist with Thunberg’s climate movement Fridays For Future, which is organizing the march. The COP26 talks in Glasgow aimed to secure enough national promises to cut greenhouse gas emissions – mainly from fossil fuels – to keep the rise in the average global temperature to 1.5 degrees Celsius. Crossing that threshold could trigger a cascading climate crisis, scientists say. The COP26 summit has so far yielded deals to phase out coal, reduce deforestation and curb methane, but a clear picture has yet to emerge on what these voluntary initiatives would add up to in terms of moderating temperature rises. The head of the International Energy Agency, Fatih Birol, said on Thursday that emissions cut pledges made so far – if all implemented – could …

South Korea Showed How to Contain COVID, Now It Will Try to Live With It

Seats are once again packed at professional baseball games in South Korea. Just as in pre-pandemic times, fans can drink beer and eat fried chicken. They can clap their hands, stomp their feet, and wave inflatable noisemakers to support their team. What they are not allowed to do, though, at least not yet, is shout or sing fight songs, a key feature of Korean baseball crowds. “If you shout a lot, the virus will leak through your mask,” Prime Minister Kim Boo-kyum pleaded with fans on a radio show this week, after crowds were seen as being too vocally supportive of their teams during tense playoff games. It is a microcosm of how life is going in South Korea: basically, things are returning to normal, but they are not quite there yet. Although South Korea never locked down during the coronavirus pandemic, it was never fully open either, especially as the country has battled a fourth wave of infections since July. However, starting this week, the government rolled out the first step of its “living with COVID-19” plan. Bigger crowds can now gather in Seoul. Restaurants and cafes, including those that serve alcohol, are no longer subject to a nighttime curfew. Sports fans have returned to stadiums and arenas. Barring setbacks, South Korea will phase out all social distancing rules by the end of February, two years after the country experienced one of the world’s first COVID-19 outbreaks. South Korea’s COVID-19 approach has unquestionably been a success so far. It …

French Film Festival Highlights African Water Problem

A documentary about the impact of climate change in Africa is a highlight of the annual French film festival in Los Angeles this year. The festival, “City of Light, City of Angels,” draws filmmakers from Paris and fans from Los Angeles. Mike O’Sullivan reports on the documentary “Marcher sur L’eau” (released in English as “Above Water”), which is causing a buzz. …

Why US Consumers Pay Such High Prices for Prescription Drugs 

Congressional Democrats this week proposed an addition to U.S. President Joe Biden’s climate and social spending legislation that would allow Medicare, the federal government’s health care program for older Americans, to negotiate with drugmakers over the cost of certain prescription medications. U.S. consumers pay higher prices for prescription medications than almost any of their peers in the developed world, a fact that generations of politicians and advocates have struggled in vain to change. If passed, the proposal working its way through Congress would make a dent, though a relatively small one, in that long-standing problem. The plan being discussed would give Medicare officials the ability to negotiate pricing on a sliver of the thousands of prescription medications on the market in the United States, beginning with about 10 drugs and capped at 20. Liberal members of Congress at first had hoped to grant Medicare authority to negotiate the prices of up to 250 costly drugs every year. Though small, the number of drugs that would be covered by the proposal represents a disproportionate amount of the annual “spend” on drugs by Medicare patients. A study by the Kaiser Family Foundation released this year determined that the 10 top-selling drugs covered under Medicare Part D accounted for 16% of net total spending in 2019. The top 50 drugs — representing just 8.5% of all drugs covered under the program — accounted for 80% of spending. The top 10 drugs, according to the Kaiser Family Foundation include “three cancer medications, four diabetes …

Senior UNICEF Official in Zimbabwe Assesses Funded Projects

Belinda Kaziwisi of Mount Darwin, Zimbabwe, about 200 kilometers north of Harare, is among the Zimbabwean mothers seeing the benefits that have grown from money provided by UNICEF. “What I see has changed for the better is that from when I got pregnant until up to the delivery of my child, I didn’t pay anything,” Kaziwisi said, her healthy baby in her arms. “When I delivered, I was given soap, cotton and other things for free. It was all nice compared with what used to happen before.” With funding from UNICEF, the Zimbabwe government has hired health workers who encourage pregnant mothers in rural villages to seek assistance from the country’s health institutions to avoid complications. “We encourage pregnant mothers to come to clinics,” said Letty Chindundu, one of the health workers. “We tell them: When you get to the third month of your pregnancy, please go to the clinic. Health workers there will tell you what to do. The journey to delivery of your baby becomes easy. Even your baby will be taken care of while in the tummy, since there are now so many diseases. If they do not come to clinic, the baby may be delivered with ailments. That’s how we encourage them to come to clinic — when they [become] pregnant.” Dr. Tajudeen Oyewale, the UNICEF representative in Zimbabwe, said that having health workers in rural villages and funding the country’s health sector are paying off. “[According to] the latest results of the Multiple Indicator Cluster Survey, …

UK Gears Up to Produce Rare Earth Magnets, Cut Reliance on China 

Britain could revive domestic production of super strong magnets used in electric vehicles and wind turbines with government support, to cut its reliance on China and achieve vital cuts in carbon emissions, two sources with direct knowledge said.  A government-funded feasibility study is due to be published on Friday, laying out the steps Britain must take to restart output of rare earth permanent magnets, the sources said.  A magnet factory would help Britain, hosting the COP26 U.N. climate talks in Glasgow, Scotland, meet its goal of banning petrol and diesel cars by 2030 and slashing carbon emissions to net zero by 2050.  British production of the magnets vanished in the 1990s when the industry found it could not compete with China. But with the huge growth in demand, the government is keen to secure enough supply.  Last month, the government set out plans to achieve its net zero strategy, which includes spending $1.15 billion to support the roll out of electric vehicles (EVs) and their supply chains.  The study outlines how a plant could be built by 2024 and eventually produce enough of the powerful magnets to supply 1 million EVs a year, the sources who have read the report said.  “We’re looking to turn the tide of shipping all this kind of manufacturing to the Far East and resurrect U.K. manufacturing excellence,” one of the sources said.  The government’s Department for Business declined to comment on details regarding a possible magnet factory because the report has not been released.  …

Foreign Children of Islamic State Detained in Northeastern Syria Face Bleak Future

When Islamic State militants took over territory in Syria and Iraq, fighters from around the world joined them, often bringing children too young to know where they were going or why. Now, years later with these fighters in captivity, many of their children remain in Syria, locked up and abandoned by their home countries. VOA’s Heather Murdock reports from Tal Marouf in northeastern Syria. …

American Nurses: Stop Assaulting Us!

Regularly cursed at and sometimes physically assaulted by patients, nurses in the U.S. have had enough. As VOA’s Veronica Balderas Iglesias reports, the pandemic is accelerating a longstanding problem of violence against frontline health care workers. A warning: some images in this report may be disturbing. …

New Zealand Researchers Hope to Replace Fossil Fuel Use in Antarctica With Green Hydrogen

A New Zealand research project is looking at ways to produce hydrogen in Antarctica to reduce carbon emissions.   A four-month New Zealand project is investigating whether hydrogen could be generated, used and stored at Scott Base, its Antarctic research facility, to reduce its reliance on carbon-based fuels.  Those fuels are currently used for transportation, cooking and heating.  A special grade fuel is shipped in on ice-breakers.   Surplus power from wind turbines at Scott Base could be used to generate green hydrogen for hydrogen fuel cells that produce electricity by combining hydrogen and oxygen atoms.   The hydrogen initiative is a collaboration between Antarctica, New Zealand, a government scientific body, and the University of Canterbury in Christchurch.  The project started in August and will finish this month.  The project faces some obstacles, including geographic isolation and extreme weather. Antarctica is the coldest, windiest and driest continent. In 1983, a temperature of minus 89.2 degrees was recorded.  Brendon Miller, a consultant chemical engineer, says it is an ambitious plan.   “We would like to demonstrate that we can use hydrogen effectively as an energy source to replace fossil fuels. It is a very challenging environment to do it in Antarctica. But, actually, there are some things going for it because the alternates like batteries are quite awkward to use for long-term storage particularly at very cold temperatures,” Miller said.   New Zealand’s work in Antarctica focuses in large part on global warming.    Experts have said the world’s southernmost continent was very sensitive to rising temperatures, and it also influenced the global climate system.  Earlier this year, the New Zealand government said it would spend  $200 million to guarantee the future of its scientific hub at Scott …

Study Shows COVID-19 Pandemic Diminished Life Expectancy Around the Globe in 2020

The COVID-19 pandemic shortened life expectancy around the globe last year, according to a new international study. A team of researchers led by University of Oxford public health professor Nazur Islam examined changes to life expectancy in 37 upper-middle- and high-income countries, using the years between 2005 and 2019 as a benchmark, and compared the ages of the deceased to their life expectancies. The study, published this week in the scientific journal BMJ, found that Russia had the highest drop in life expectancy, where men lost 2.33 years and women 2.14 years. In second place was the United States, with men losing 2.27 years and women 1.61 years, followed by Bulgaria with men losing 1.96 years and women 1.37 years. A total of 31 nations saw declines in life expectancy. According to the researchers, these countries’ populations lost about 28 million additional years of life. Six nations — Denmark, Iceland, New Zealand, Norway, South Korea and Taiwan — were the only nations of those studied where life expectancy either increased or remained the same. The researchers say most countries in Asia, Africa and Latin America were not included in the study due to a lack of data, meaning the true toll from the pandemic was likely even higher. The pandemic has claimed more than 5 million lives since the first cases were detected in central China in late 2019, with the United States the world leader in COVID-19 deaths with 750,430, according to Johns Hopkins Coronavirus Resource Center. Meanwhile, vaccinations of children between 5 and 11 years of age began in earnest across the United States Wednesday, just …

What Are the Facebook Papers?

Social media behemoth Facebook is facing public and regulatory scrutiny after the disclosure of thousands of pages of internal documents by a whistleblower who used to work for the company. What are the Facebook papers? After compiling the documents while working as a Facebook product manager, Frances Haugen distributed them to a group of 17 U.S. news organizations that collaborated on a project to individually publish stories on their findings. The stories, released on a coordinated day in late October, portray Facebook as pursuing audience growth and profits while ignoring how people were using the platform to spread hate and misinformation. The documents showed Facebook particularly struggled with monitoring for hate speech, inflammatory rhetoric and misinformation by users posting in certain countries, including some that Facebook had determined were at the most risk for real-world consequences of such abuses. The failures included both inadequate artificial intelligence systems and not enough human moderators who speak the many languages spoken by Facebook users. Who else received them? In addition to providing the documents to journalists, Haugen has also made them available to the U.S. Securities and Exchange Commission and the U.S. Congress. Haugen has also appeared before the Senate Commerce Committee and testified before the British Parliament. Haugen used her smartphone camera to capture the documents. Why are they important? The company has massive global reach. Facebook had 2.74 billion active users as of the end of September, according to company statistics. That is about 1 out of every 3 people on …

How COVID-19 Stole ‘Children’s Joy,’ Sparking a Mental Health Emergency

No in-person school. Isolation from friends. Lost rites of passage like graduation ceremonies. The COVID-19 pandemic upended the lives of many children in the United States. “A lot of children’s joy comes from being with friends or from play, and from social interaction. When you ask kids, ‘What’s making you happy?’ 90% of the time, it’s being around friends or doing things with friends,” says Elena Mikalsen, head of the Psychology Section at the Children’s Hospital of San Antonio in Texas. “That was kind of taken away during the pandemic. … For the longest time, all kids had was the academics and no joy.”  A recent report finds that the uncertainty and disruption caused by COVID-19 has negatively affected the emotional and mental health of about one-third of America’s youth. So much so that the American Academy of Pediatrics (AAP), along with other children’s health organizations, has declared a national emergency in child and adolescent mental health. “Elevated symptoms of anxiety, depression or stress,” says Nirmita Panchal, a senior policy analyst at the Kaiser Family Foundation (KFF), a nonprofit organization focusing on national health issues. “There’s also been a number of changes in behavior that parents have reported with some children having a poor appetite and difficulty sleeping. For others, it may be fear or irritability and clinginess.” Panchal co-authored the report, which found that 8% of children between the ages of 3 and 17 currently have anxiety. That number rises to 13% among adolescents ages 12 to 17. “During the pandemic, children, just like everybody else, have experienced a number of …

US Blacklists Four Foreign Companies for ‘Malicious Cyber Activities’

The U.S. government has added four foreign technology companies to its restricted companies list, saying they “developed and supplied spyware to foreign governments” and that the spyware was used “to maliciously target government officials, journalists, businesspeople, activists, academics, and embassy workers.” The State Department accused the companies of “engaging in activities contrary to the national security or foreign policy interests of the United States.”  The companies are Israel’s NSO Group and Candiru, Russia’s Positive Technologies, and Singapore’s Computer Security Initiative Consultancy PTE. LTD.  These companies will now face severe restrictions in exporting their products to the U.S., and it will make it difficult for U.S. cybersecurity firms to sell them information that could be useful in developing their products.  “This effort is aimed at improving citizens’ digital security, combating cyber threats, and mitigating unlawful surveillance,” the State Department said.  According to Reuters, both NSO Group and Candiru have been accused of selling their products to authoritarian regimes. NSO said it takes actions to prevent the abuse of its products.  Positive Technologies has been in the crosshairs before, having been sanctioned by the Biden administration for allegedly providing assistance to Russian security forces. The company said it has done nothing wrong.  None of the companies commented on their blacklisting.    Some information in this report comes from Reuters.    …

COP26: Will Vaccine Inequality Drive Distrust Between Rich, Poor Nations at Climate Summit?

The COP26 climate summit is taking place against the backdrop of an ongoing global pandemic. As richer nations begin to reopen, thanks to rapid vaccination programs, most people in developing countries are still waiting for their first dose, despite global pledges to distribute more vaccines. Analysts say distrust between richer and poorer nations could hamper climate negotiations at the COP26 summit.  In most high-income countries, more than 70% of the population has received at least one dose of a COVID-19 vaccine. But in low-income countries, the figure is less than 4%, according to figures from the University of Oxford.  “If this level of vaccine inequity remains in place, 5 million people will die unnecessarily next year,” said Robert Yates, director of the global health program at Chatham House.    At the G-7 summit in June, leaders of the world’s richest nations pledged to share 1 billion vaccine doses with poorer countries — half from the United States. In total, the U.S. has now pledged to share 1.1 billion doses through 2022. Yet, while many Western nations are offering a third booster shot for fully vaccinated adults, most people in developing nations still await their first dose. As negotiations on combating climate change continue at the COP26 summit in Glasgow, trust between poorer and richer nations is fragile, Yates said.  “You can very much see countries, particularly in the South, saying, ‘Well, why should we cooperate with you on this issue which is happening now but is going to get worse …

COP26: Will Vaccine Inequality Drive Distrust Between Rich, Poor Nations at Climate Summit?

The COP26 climate summit is taking place against the backdrop of an ongoing global pandemic. As richer nations begin to reopen thanks to rapid vaccination programs, most people in developing countries are still waiting for their first dose. Henry Ridgwell reports from the summit in Glasgow on whether distrust between richer and poorer nations could hamper climate negotiations.  Camera: Henry Ridgwell     Produced by: Kimberlyn Weeks …